業績ACHIVEMENT

2016年～現在

2015年以前の論文はこちら
2010年以前の論文はこちら
2005年以前の論文はこちら

研究論文

  • Nakai, R., Kusada, H., Sassa, F., Morigasaki, S., Hayashi, H., Takaya, N., Tamaki, H.: Genomic insights into a novel filterable Rhodospirillales bacterium strain TMPK1 isolated from soil. (MRA00393-21)
  • A.Nag., M.A.Ali., H.Kawaguchi., S.Saito., Y.Kawasaki., S.Miyazaki., H.Kawamoto., D.T.N.Adi., K.Yoshihara., S.Masuo., Y.Katsuyama., A.Kondo., C.Ogino., N.Takaya., T.Kaneko., Y.Ohnishi.,: Ultrahigh Thermoresistant Lightweight Bioplastics Developed from Fermentation Products of Cellulosic Feedstock. Adv. Sus. Sys., 5, 2000193 (2020)
  • Kanazawa, H., Ozaki, S., Doi, Y., Masuo, M., Takaya, N.: Symbiotic riboflavin degradation by Microbacterium and Nocardioides bacteria. Biosci. Biotechnol. Biochem. 84, 1056-1061 (2020)
  • Masuo, S., Tsuda, Y., Namai,T., Minakawa, H., Shigemoto, R., Takaya, N.: Enzymatic cascade in Pseudomonas for pyrazine production from α-amino acids. ChemBioChem, 21, 353-359 (2020)
  • Yang, Y., Zhou, Y., Li, J., Yu, H., Takaya, N., Wang, P., Zhou, S.: Novel peroxiredoxin-based sensor for sensitive detection of hydrogen peroxide. Biochem Biophys Res Commun. (2019)
  • H, Kawaguchi., H, Miyagawa., S, Nakamura-Tsuruta., N, Takaya., C, Ogino., A, Kondo.: Enhanced phenyllactic acid production in Escherichia coli via oxygen limitation and shikimate pathway gene expression. Biotechnology Journal, 14, e1800478 (2019)
  • Minakawa, H., Masuo, S., Kaneko, T., Takaya, N.: Fermentation and purification of the microbial monomer 4-amminocinnamic acid for producing ultra-high performance plastics. Process Biochem. 77, 100-105 (2019)
  • Sakai, K., Matsuzaki, F., Wise, L., Sakai, T., Jindou, S., Ichinose, H., Takaya, N., Kato, M., Wariishi, H., and Shimizu, M.: Biochemical characterization of CYP505D6, a self-sufficient cytochrome P450 from the white-rot fungus Phanerochaete chrysosporium. Appl. Environ. Microbiol., 84, e01091-01118
  • Kanazawa, H., Shigemoto, R., Kawasaki, Y., Oinuma, K.-I., Nakamura, A., Masuo, S., Takaya, N.: Two-component flavin-dependent riboflavin monooxygenase degrades riboflavin in Devosia riboflavina. J. Bacteriol., 200, e00022-18 (2018)
  • Shigemoto, R., Matsumoto, T., Masuo, S., Takaya, N.: 5-Methylmellein is a novel inhibitor of fungal sirtuin and modulates fungal secondary metabolite production. J. Gen. Appl. Micorbiol.,64, 240-247 (2018)
  • Oinuma, K.-I., Yamaguchi, I., Shindo, D., Fujimoto, M., Nishiyama, T., Takano, H., Takaya, N., Ueda, K.: Extracytoplasmic diaphorase activity of Streptomyces coelicolor A3(2). Biochem Biophys Res Commun. 10;503(3): 1581-1586 (2018)
  • Shigemoto, R., Oinuma, K.-I., Masuo, S., Takaya, N.: Novel antioxidant isolated from Warcupiella spinulosa JCM 2358, 7-hydroxycordylactam. Heterocycles, 96, 1075-1079 (2018)
  • Masuo, S., Komatsuzaki, A., Takeshita, N., Ito, E., Okazoe, Zhou, S., Takaya, N.: Heterogeneous localization of glycogen and its metabolizing enzymes in Aspergillus nidulans hyphae. Fungal Genet. Biol. 110, 48-55 (2018)
  • Kawasaki, Y., Aniruddha, N., Minakawa, H., Masuo, S., Kaneko, K., Takaya, N.: Novel poly-condensed biopolyamide generated from biomass-derived 4-aminohydrocinnamic acid. Appl. Microbiol. Biotechnol. 108, 631-639 (2018)
  • Xia, Y., Yu, H., Zhou, Z., Takaya, N., Zhou, S., Wang, P.: Peroxiredoxin system of Aspergillus nidulans resists inactivation by high concentration of hydrogen peroxide-mediated oxidative stress. J. Microbiol. Biotechnol., 28, 145-156 (2018)
  • Takeshita, N., Evangelinos, M., Zhou, L., Serizawa, T., Somera-Fajardo, R. A., Lu, L., Takaya, N., Nienhaus, G. U., and Fischer, R.: Pulses of Ca2+ coordinate actin assembly and exocytosis for stepwise cell extension. Proc. Natl. Acad. Sci. USA, 114, 5701-5706 (2017)
  • Itoh, E., Odakura, R., Oinuma, K.-I., Shimizu, M., Masuo, S., Takaya, N.: Sirtuin E is a fungal global transcriptional regulator that determines the transition from the primary growth to the stationary phase. J. Biol. Chem. 292, 11043-11054 (2017)
  • Akiyama, T., Ishii, M., Takuwa, A., Oinuma, K.-I., Sasaki, Y., Takaya, N., Yajima, S.: Structural basis of the substrate recognition of hydrazidase isolated from Microbacterium sp. strain HM58-2, which catalyzes acylhydrazide compounds as its sole carbon source. Biochem Biophys Res Commun. 482, 1007-1012 (2017)
  • Itoh, E., Shigemoto, R., Oinuma, K.-I., Shimizu, M., Masuo, S., Takaya, N.: Sirtuin A regulates secondary metabolite production by Aspergillus nidulans. J. Gen. Appl. Micorbiol., 63, 228-235 (2017)
  • Akiyama, T., Yamada, Y., Takaya, N., Ito, S., Sasaki, Y., Yajima, S.: Crystal structure of an IclR homologue from Microbacterium sp. strain HM58-2. Acta Crystallogr F Struct Biol Commun. 73, 16-23 (2017)
  • Takeshita, N., Evangelinos, M., Zhou, L., Serizawa, T., Somera-Fajardo, R. A., Lu, L., Takaya, N., Nienhaus, G. U., and Fischer, R.: Pulses of Ca2+ coordinate actin assembly and exocytosis for stepwise cell extension. Proc. Natl. Acad. Sci. USA, (in press, 2017)
  • Itoh, E., Odakura, R., Oinuma, K.-I., Shimizu, M., Masuo, S., and Takaya, N.: Sirtuin E is a fungal global transcriptional regulator that determines the transition from the primary growth to the stationary phase. J. Biol. Chem. (in press, 2017)
  • Akiyama T, Ishii M, Takuwa A, Oinuma KI, Sasaki Y, Takaya N, Yajima S.: Structural basis of the substrate recognition of hydrazidase isolated from Microbacterium sp. strain HM58-2, which catalyzes acylhydrazide compounds as its sole carbon source. Biochem Biophys Res Commun. 482, 1007-1012 (2017)
  • Itoh, E., Shigemoto, R., Oinuma, K.-I., Shimizu, M., Masuo, S., and Takaya, N.: Sirtuin A regulates secondary metabolite production byAspergillus nidulans. J. Gen. Appl. Micorbiol. (in press, 2017)
  • Akiyama T, Yamada Y, Takaya N, Ito S, Sasaki Y, Yajima S.: Crystal structure of an IclR homologue from Microbacterium sp. strain HM58-2. Acta Crystallogr F Struct Biol Commun. 73, 16-23 (2017)
  • Masuo, S., Kobayashi, Y., Oinuma, K.I., and Takaya, N.: Alternative fermentation pathway via phanyllactic acid produces cinnamic acid. Appl. Microbiol. Biotechnol. 100, 8701-8709 (2016)
  • Masuo, S., Zhou, S., Kaneko, T., and Takaya, N.: Bacterial fermentation platform for producing artificial aromatic amines. Sci. Rep. 6, 25764 (2016)
  • Shimizu, M., Masuo, S., Ito, E., and Takaya, N.: Thiamine synthesis regulates the fermentation mechanisms in the fungus Aspergillus nidulans. Biosci. Biotechnol. Biochem. 11, 1-8 (2016)
  • Tateyama, S., Masuo, S., Suvannasara, P., Oka, Y., Miyazato, A., Yasaki, K., Teerawatananond, T., Muangsin, N., Zhou, S., Kawasaki, Y., Zhu, L., Zhou, Z., Takaya, N., and Kaneko, T.: Ultrastrong, transparent polytruxillamides derived from microbial photodimers. Macromolecules 49, 3336−3342 (2016)
  • Sasaki, Y., Oguchi, H., Kobayashi, T., Kusama, S., Sugiura, R., Moriya, K., Hirata, T., Yukioka, Y., Takaya, N., Yajima, S., Ito, S., Okada, K., Osawa, K., Ikeda, H., Takano, H., Ueda, K., and Shoun, H.: Nitrogen oxide cycle regulates nitric oxide and bacterial cell signaling. Sci. Rep. 6, 22038 (2016)
  • Akiyama, T., Ishige, T., Kanesaki, Y., Ito, S., Oinuma, K. I., Takaya, N., Sasaki, Y., Yajima, S.: Draft genome sequence of Microbacterium sp. strain HM58-2 that catabolites acylhydrazides. Genome Announcement 4, e00554-16. (2016)
  • Kumar, A., Tateyama, S., Yasaki, K., Ali, A.M., Takaya, N., Singh, R., and Kaneko, T.: 1H-NMR and FT-IR dataset based structural investigation of poly(amic acid)s and polyimides from 4,4′-diaminostilbene. Data in Brief 7, 123-128 (2016)
  • Kumar, A., Tateyama, S., Yasaki, K., Ali, M. A.., Takaya, N., Singh, R., and Kaneko, T.:Ultrahigh performance bio-based polyimides from 4,4′-diaminostilbene. Polymer, 83, 182-189 (2016)
  • Nguyen, H. D., Kaneko, T., Takaya, N., Fujita, T., Ito, T.: Fermentation of aromatic lactate monomers and its polymerization to produce highly thermoresistant bioplastics.Polymer J. 48, 81-89 (2016)
  • Shimizu, M., Yamamoto, T., Okabe, N., Sakai, K., Koide, E., Miyachi, Y., Kurimoto, M., Mochizuki, M., Yoshino-Yasuda, S., Mitsui, S., Ito, A., Murano, H., Takaya, N., Kato, M.: Novel 4-methyl-2-oxopentanoate reductase involved in synthesis of the Japanese sake flavor, ethyl leucate. Appl. Microbiol. Biotechnol. 100, 3137-3145 (2016)

総説

  • 老沼研一、高谷直樹：ヒドラジン類縁化合物の微生物代謝―明らかとなった新規分解機構、化学と生物
  • 桝尾俊介、土肥裕希、高谷直樹：酸化ストレスに強いカビと細菌のストレス耐性機構、生物工学会誌2015年8号、457-459 (2015)
  • 金子達雄、高谷直樹：セ氏425度という高温に耐えられるバイオプラスチックを開発―微生物と光化学反応によるポリイミド合成、化学と生物、53、270-272 (2015)
  • 周勝敏、高谷直樹：ニトロソチオネインの発見と真菌の一酸化窒素耐性化、バイオサイエンスとインダストリー、72, 132-133 (2014)
  • 桝尾俊介、老沼研一、高谷直樹: 多様な微生物代謝を利用した芳香族バイオ素材の開発、ケミカルエンジニヤリング(2013)
  • Takaya, N.: Response to hypoxia, reduction of electron acceptors, and subsequent survival by filamentous fungi,Biosci. Biotech. Biochem.73, 1-8 (2009)
  • 安部剛史、高谷直樹：カビによる新規な異化代謝の機能解明とその利用の可能性、J. Environmental Biotechnology.6, 79-85 (2007)
  • 高谷直樹、志水元亨：息づまる闘い－カビの生き残り戦略？、生物工学会誌、85、416 (2007)
  • 高谷直樹、祥雲弘文：低酸素環境下でのカビの呼吸と発酵、バイオサイエンスとインダストリー、63、233-236 (2005)佐々木康幸、高谷直樹、祥雲弘文：廃水からの窒素除去システムの現状と展望、生物工学会誌、83、202 (2005)
  • 高谷直樹、祥雲弘文：低酸素状態でのカビの生き残り戦略―わかってきたカビ脱窒系の役割。呼吸系の進化や窒素サイクルを考えるヒントに、化学と生物、40巻，356-358 (2002)
  • Takaya, N.: Dissimilatory nitrate reduction metabolisms and their control in fungi, J. Biosci. Bioeng. 94, 506-510 (2002)
  • Zhou, Z., Takaya, N., and Shoun, H.: Denitrification by eukaryotic microorganisms, Recent Research Developments in Microbiology, vol. 6, 259-268, Research Signpost, Kerala, India (2002)
  • Takaya, N., Horiuchi, H., and Takagi, M.: 糸状菌による異種蛋白質生産の現状と展望, 食品工業 37巻, 16-21 (1994).

著書

  • Zhang, L., Kudo, T., Takaya, N., and Shoun, H.: Distribution, structure and function of fungal nitric oxide reductase P450nor-recent advances, in Excerpta Medica International Congress Series vol. 1233, p197-202, Y. Ishimura, M. Nozaki, S. Yamamoto, T. Shimizu, S. Narumiya, and F. Mitani,. Eds., Elsevier, Amsterdam, The Netherlands (2002).
  • Shoun H., and Takaya, N.: Cytochrome P450nor and P450foxy from the fungus Fusarium oxysporum, in Excerpta Medica International Congress Series vol. 1233, p89-97, Y. Ishimura, M. Nozaki, S. Yamamoto, T. Shimizu, S. Narumiya, and F. Mitani,. Eds., Elsevier, Amsterdam, The Netherlands (2002).
  • Kitazume, T., Tanaka, A., Matsuyama, S., Takaya, N. and Shoun, H.: Analysis of fungal P450foxy (CYP505), a fused protein of cytochrome P450 and its reductase. in Excerpta Medica International Congress Series vol. 1233, p143-149, Y. Ishimura, M. Nozaki, S. Yamamoto, T. Shimizu, S. Narumiya, and F. Mitani,. Eds., Elsevier, Amsterdam, The Netherlands (2002).
  • Takaya, N., Kobayashi, M., and Shoun, H.: Fungal denitrification, possible occurrence of a natural horizontal gene transfer from prokaryote to eukaryote. in ‘Proceedings of Fallen Leaf Conference on Horizontal Gene Transfer: Implications and Consequences’ eds. M. Syvanen and C. Kado, Chapsman & Hall, p321-327 (1998).
  • Takaya, N., Kudo, T., and Shoun, H.: Analysis of NAD(P)H binding site of cytochrome P450nor. in ‘Oxygen homeostasis and its dynamics’ Ishimura, Ed., Springer-Verlag Tokyo, Tokyo, Japan. p163-167 (1997).

受賞

  • 若手口頭発表部門優秀発表賞：金澤拓史, 柳榮美, 高谷直樹
    環境中のビタミン恒常性を担う複合微生物系
    日本農芸化学会関東支部大会(平成27年9月)、つくば
  • ポスター賞受賞：阿部央行，桝尾俊介，高谷直樹
    Aspergillus nidulans の低酸素誘導性脱ユビキチン化酵素の機能
    第14回糸状菌分子生物学コンファレンス（平成26年11月)、仙台
  • ポスター賞受賞：中澤奈美，老沼研一，高谷直樹
    糸状菌 Aspergillus nidulans による土壌フミン酸の代謝機構
    第13回糸状菌分子生物学コンファレンス（平成25年11月)、つくば
  • ポスター賞受賞：伊藤英里子、志水元亨、桝尾俊介、高谷直樹
    Aspergillus nidulans の sirtuin 様タンパク質 SirA の機能解析
    第12回糸状菌分子生物学コンファレンス（平成24年11月)、名古屋
  • 若手奨励賞：上村曜介、鳴神寿昭、桝尾俊介、高谷直樹
    糸状菌 Aspergillus nidulans の二次代謝産物生合成における転写因子AmyRの役割
    日本農芸化学会関東支部大会(平成23年10月)、群馬
  • ポスター賞受賞：上村曜介、鳴神寿昭、桝尾俊介、高谷直樹
    転写因子AmyRが Aspergillus nidulans の二次代謝に及ぼす影響の解析
    第10回糸状菌分子生物学コンファレンス（平成22年11月)、広島
  • 日本醸造学会若手の会ポスター賞受賞：上村曜介、鳴神寿昭、桝尾俊介、高谷直樹
    転写因子AmyRが Aspergillus nidulans の二次代謝に及ぼす影響の解析
    日本醸造学会若手の会（平成22年9月）、東京
  • 第21回日本微生物生態学会大会優秀ポスター発表賞：豊福雅典・野村暢彦・高谷直樹・藤井達也・中島敏明・内山裕夫
    Pseudomonas aeruginosa における細胞間情報伝達シグナルの脱窒への関与（2005年11月）

2015年以前の論文

  • Doi, Y., and Takaya, N.: A novel A3 group aconitase tolerating oxidation and nitric oxide. J. Biol. Chem. 290, 1412-1421 (2015)
  • M., Sakai, K., Yamada, M., Murata, S., Itoh, E., Yamamoto, T., Sugimura, Y., Hirano, T., Takaya, N., Kobayashi, T., and Kato, M.: Novel b-1,4-mannanase belonging to a new glycoside hydrolase family in Aspergillus nidulans. J. Biol. Chem. 27914-27927 (2015)
  • Oinuma, K.I., Takuwa, A., Doi, Y., and Takaya, N.: Hydrazidase; A novel amidase signature enzyme that hydrolyzes acylhydrazides. J. Bacteriol. 197, 1115-1124 (2015)
  • Masuo, S., Osada, L., Zhou, S., Fujita, T., and Takaya, N.: Aspergillus oryzae pathways for converting phenylalanine into flavor volatile 2-phenylethanol. Fungal Genet. Biol. 77, 22-30 (2015)
  • Kawaguchi, H., Teramura, K., Uematsu, K., Hara, Y., Hasunuma, T., Hirano, K., Sazuka, T., Kitano, H., Tsuge, Y., Kahar, P., Niimi-Nakamura, S., Oinuma, K.-I., Takaya, N., Kasuga, S., Ogino, C., and Kondo, A.: Phenyllactic acid production by simultaneous saccharification and fermentation of pretreated sorghum bagasse. Bioresource Technol. 182, 169-178 (2015)
  • Graminho, E., Takaya, N., Nakamura, A., and Hoshino, T.: Purification, biochemical characterization, and genetic cloning of the phytase produced by Burkholderia sp. strain a13. J. Gen. Appl. Micorbiol. 61, 15-23 (2015)
  • Doi, Y., Shimizu, M., Fujita, T., Nakamura, A., Takizawa, N., and Takaya, N.: Achromobacter denitrificans YD35 pyruvate dehydrogenase controls NADH production to tolerate extremely high nitrite levels. Appl. Environ. Microbiol. 80, 1910-1918 (2014) [Selected as "Spotlight"]
  • Toyofuku, M., Zhou, S., Sawada, I., Takaya, N., Uchiyama, H., and Nomura, N.; Membrane vesicle formation is associated with pyocin production under denitrifying conditions in Pseudomonas aeruginosa PAO1, Environment. Microbiol. 16, 2927-2938 (2014)
  • Suvannasara, P., Tateyama, S., Miyazato, A., Matsumura, K., Shimoda, T., Ito, T., Fujita, T., Yamagata, Y., Takaya, N., Kaneko, T.: Bio-based polyimides from 4-aminocinnamic acid photodimer. Macromolecules. 47, 1586-1593 (2014)
  • Siriwan, W., Takaya, N., Roytrakul, S., and Chowpongpang, S.: Study of interaction between Papaya ringspot virus HC-Pro and Papaya (Carica papaya) Proteins. J. Gen. Plant Pathol. 80, 264-271 (2014)
  • Sasaki, Y., Takaya, N., Morita, A., Nakamura, A., and Shoun, H.: Nitrite formation from organic nitrogen by Streptomyces antibioticus supporting bacterial cell growth and possible involvement of nitric oxide as an intermediate. Biosci. Biotechnol. Biochem. 78, 1592-1602 (2014)
  • Kawaguchi, H., Uematsu, K., Ogino, C., Teramura, H., Niimi-Nakamura, S., Tsuge, Y., Hasunuma, T., Oinuma, K. Takaya, N., and Kondo, A. Simultaneous saccharification and fermentation of kraft pulp by recombinant Escherichia coli for phenyllactic acid production. Biochem. Eng. J. 88, 188-194 (2014)
  • Zhou, S., Narukami, T., Masuo, S., Shimizu, M., Fujita, T., Kamimura, Y., and Takaya, N.: NO-inducible nitrosothionein mediates NO removal in tandem with thioredoxin. Nat. Chem. Biol. 9, 657-663 (2013)
  • Fujita, T., Nguyen, Nieu Duc, Ito, T., Zhou, S., Osada, L., Tateyama, S., Kaneko, T., and Takaya, N.: Microbial monomers custom-synthesized to build true bio-derived aromatic polymers.Appl. Microbiol. Biothechnol. 97, 8887-8894 (2013)
  • Shimizu, M., and Takaya, N.: Nudix hydrolase controls nucleotides and glycolytic mechanisms in hypoxic Aspergillus nidulans. Biosci. Biotechnol. Biochem. 77, 1888-1893 (2013)
  • Sugimoto, N., Takakura, Y., Shiraki, K., Honda, S., Takaya, N., Hoshino, T., and Nakamura, A.: Directed Evolution for Thermostabilization of a Hygromycin B Phosphotransferase from Streptomyces hygroscopicus. Biosci. Biotechnol. Biochem. 77, 2234-2241 (2013)
  • Siriwan, W., Roytrakul, S., Shimizu, M., Takaya, N., and Chowpongpang, S.: Proteomics of papaya ringspot virus-infected papaya leaves. Kasetsart J. (Nat. Sci.) 47, 589-602 (2013)
  • Shimizu, M., Masuo, S., Fujita, T., Doi, Y., Kamimura, Y., Takaya, N.: Hydrolase controls cellular nicotinamide adenine dinucleotide, sirtuin and secondary metabolites. Mol. Cell. Biol. 32, 3743-3755 (2012)
  • Shimizu, T., Takaya, N., Nakamura, A.: An L-glucose catabolic pathway in Paracoccus sp. 43P, J. Biol. Chem. 287, 40448-40456 (2012)
  • Taniyama, K., Sasaki, Y., Toyofuku, M., Nomura., N., Itoh, H., Hoshino, T., and Takaya, N.: Group X aldehyde dehydrogenases of Pseudomonas aeruginosa PAO1 degrade hydrazones. J. Bacteriol.194, 1447-1456 (2012)
  • Zhou, S., Narukami, T., Nameki, M., Ozawa, T., Kamimura,Y., Hoshino, T., and Takaya, N.: Heme-biosynthetic porphobilinogen deaminase protects Aspergillus nidulans from nitrosative stress. Appl. Environ. Microbiol. 78, 103-109 (2012)
  • Terabayashi, Y., Shimizu, M., Kitazume, T., Masuo, S., Fujii, T., and Takaya, N.: Conserved and specific responses to hypoxia in Aspergillus oryzae and Aspergillus nidulans determined by comparative transcriptomics. Appl. Microbiol. Biothechnol. 93, 305-317 (2012)
  • Fujii, T., Shimizu, M., Doi, Y., Fujita, T., Ito, T., Miura, D., Wariishi, and Takaya, N.: Novel fungal phenylpyruvate reductase belongs to D-isomer-specific 2-hydroxyacid dehydrogenase family. Biochim. Biophys. Acta. 1814, 1669-1676 (2011)
  • Sato, I., Shimatani, K., Fujita, K., Abe, T., Shimizu, M., Fujii, T., Hoshino, T., and Takaya, N.: Glutathione reductase/glutathione is responsible for cytotoxic elemental sulfur tolerance via polysulfide shuttle in fungi J. Biol. Chem. 286, 20283-20291 (2011)

2010年以前の論文

  • Shimizu, M., Fujii, T., Masuo, S., and Takaya, N.: Mechanism of de novo branched-chain amino acid synthesis as an alternative electron sink in hypoxic Aspergillus nidulans cells. Appl. Environ. Microbiol. 76, 1507-1515 (2010)
  • Masuo, S., Terabayashi, Y., Shimizu, M., Fujii, T., Kitazume, T., and Takaya, N.: Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia. Mol. Genet. Genomics. 284, 415- 424 (2010)
  • Tashiro, Y., Ichikawa, S., Shimizu, M., Toyofuku, M., Takaya, N., Nakajima-Kambe, T., Uchiyama, H., and Nomura, N.: Variation of physiochemical properties and cell association activity of membrane vesicles with growth phase in Pseudomonas aeruginosa. Appl. Environ. Microbiol. 76, 3732-3739 (2010)
  • Zhou, Z., Takaya, N., and Shoun, H: Multi-energy metabolic mechanisms of the fungus Fusarium oxysporum under lower oxygen environments. Biosci. Biotechnol. Biochem. 74, 2431-2437 (2010)
  • Sato, I., Shimizu, M., Hoshino, T., and Takaya, N.: The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase. J. Biol. Chem. 284, 8042-8053 (2009)
  • Doi, Y., Takaya, N., and Takizawa, N.: Novel denitrifying bacterium Ochrobactrum anthropi YD50.2 tolerates high levels of reactive nitrogen oxides. Appl. Environ. Microbiol. 75, 5186-5194 (2009)
  • Shimizu, M., Fujii, T., Masuo, S., Fujita, K., and Takaya, N.: Proteomic analysis of Aspergillus nidulans cultured under hypoxic conditions. Proteomics 9, 7-19 (2009)
  • Itoh, H., Suzuta, T., Hoshino, T., and Takaya, N.: Novel dehydrogenase catalyzes oxidative hydrolysis of carbon- nitrogen double bonds for hydrazone degradation. J. Biol. Chem. 283, 5790-5800 (2008)
  • Kitazume, T., Yamazaki, Y., Matsuyama, S., Shoun, H., and Takaya, N.: Production of hydroxy-fatty acid derivatives from waste oil by Escherichia coli cells producing fungal cytochrome P450foxy. Appl. Microbiol. Biothechnol. 79, 981-988 (2008)
  • Fujii, T., and Takaya, N.: Denitrification by the fungus Fusarium oxysporum involves NADH-nitrate reductase. Biosci. Biotechnol. Biochem. 72, 412-420 (2008)
  • Nakamura, A., Takakura, Y., Sugimoto, N., Takaya, N., Shiraki, K., and Hoshino, T.: Enzymatic analysis of a thermostabilized mutant of an Escherichia coli hygromycin B phosphotransferase. Biosci. Biotechnol. Biochem. 72, 2467-2471 (2008)
  • Xiang, H., Masuo, S., Hoshino, T., and Takaya, N.: Novel family of cholesterol esterases produced by actinomycetes bacteria. Biochim. Biophys. Acta, 1774, 112-120. (2007)
  • Abe, T., Hoshino, T., Nakamura, A., and Takaya, N.: Anaerobic elemental sulfur reduction by fungus Fusarium oxysporum. Biosci. Biotechnol. Biochem. 71, 2402-2407 (2007)
  • Toyofuku, M., Nomura, N., Fujii, T., Takaya, N., Maseda, H., Sawada, I., Nakajima, T., and Uchiyama, H.: Quorum sensing regulates denitrification in Pseudomonas aeruginosa PAO1. J. Bacteriol. 189, 4969-4972 (2007)
  • Suzuki, N., Takaya, N., Hoshino, T., and Nakamura, A.: Enhancement of a sB-dependent stress response in Bacillus subtilisby light via YtvA Photoreceptor. J. Gen. Appl. Microbiol. 53, 81-88 (2007)
  • Yamazaki, H., Yamazaki, D., Takaya, N., Takagi, M., Ohta, A, and Horiuchi, H.: A chitinase gene, chiB, involved in the autolytic process in Aspergillus nidulans. Curr. Genet. 51, 89-98. (2007)
  • Takaya, N., Konas, D. W., Sharma, M., and Stuehr, D. J.: Role of Asp1393 in catalysis, flavin reduction, NADP(H) binding, FAD thermodynamics, and regulation of the nNOS flavoprotein. Biochemistry, 45, 12596-12609 (2006)
  • Xiang, H., Takaya, N., and Hoshino, T.: Novel cholesterol esterase secreted by Streptomyces persists during aqueous long-term storage. J. Biosci. Bioeng. 101, 19-25 (2006)

2005年以前の論文

  • Doi, Y., and Takaya, N.: A novel A3 group aconitase tolerating oxidation and nitric oxide. J. Biol. Chem. 290, 1412-1421 (2015)
  • Shimizu, M., Kaneko, Y., Ishihara, S., Mochizuki, M., Sakai, K., Yamada, M., Murata, S., Itoh, E., Yamamoto, T., Sugimura, Y., Hirano, T., Takaya, N., Kobayashi, T., and Kato, M.: Novel b-1,4-mannanase belonging to a new glycoside hydrolase family in Aspergillus nidulans. J. Biol. Chem. 27914-27927(2015)
  • Oinuma, K.I., Takuwa, A., Doi, Y., and Takaya, N.: Hydrazidase; A novel amidase signature enzyme that hydrolyzes acylhydrazides. J. Bacteriol. 197, 1115-1124 (2015)
  • Masuo, S., Osada, L., Zhou, S., Fujita, T., and Takaya, N.: Aspergillus oryzae pathways for converting phenylalanine into flavor volatile 2-phenylethanol. Fungal Genet. Biol. 77, 22-30 (2015)
  • Kawaguchi, H., Teramura, K., Uematsu, K., Hara, Y., Hasunuma, T., Hirano, K., Sazuka, T., Kitano, H., Tsuge, Y., Kahar, P., Niimi-Nakamura, S., Oinuma, K.-I., Takaya, N., Kasuga, S., Ogino, C., and Kondo, A.: Phenyllactic acid production by simultaneous saccharification and fermentation of pretreated sorghum bagasse. Bioresource Technol. 182, 169-178 (2015)
  • Graminho, E., Takaya, N., Nakamura, A., and Hoshino, T.: Purification, biochemical characterization, and genetic cloning of the phytase produced by Burkholderia sp. strain a13. J. Gen. Appl. Micorbiol. 61, 15-23 (2015)
  • Doi, Y., Shimizu, M., Fujita, T., Nakamura, A., Takizawa, N., and Takaya, N.: Achromobacter denitrificans YD35 pyruvate dehydrogenase controls NADH production to tolerate extremely high nitrite levels. Appl. Environ. Microbiol. 80, 1910-1918 (2014) [Selected as "Spotlight"]
  • Toyofuku, M., Zhou, S., Sawada, I., Takaya, N., Uchiyama, H., and Nomura, N.; Membrane vesicle formation is associated with pyocin production under denitrifying conditions in Pseudomonas aeruginosa PAO1, Environment. Microbiol. 16, 2927-2938 (2014)
  • Suvannasara, P., Tateyama, S., Miyazato, A., Matsumura, K., Shimoda, T., Ito, T., Fujita, T., Yamagata, Y., Takaya, N., Kaneko, T.: Bio-based polyimides from 4-aminocinnamic acid photodimer. Macromolecules. 47, 1586-1593 (2014)
  • Siriwan, W., Takaya, N., Roytrakul, S., and Chowpongpang, S.: Study of interaction between Papaya ringspot virus HC-Pro and Papaya (Carica papaya) Proteins. J. Gen. Plant Pathol. 80, 264-271 (2014)
  • Sasaki, Y., Takaya, N., Morita, A., Nakamura, A., and Shoun, H.: Nitrite formation from organic nitrogen by Streptomyces antibioticus supporting bacterial cell growth and possible involvement of nitric oxide as an intermediate. Biosci. Biotechnol. Biochem. 78, 1592-1602 (2014)
  • Kawaguchi, H., Uematsu, K., Ogino, C., Teramura, H., Niimi-Nakamura, S., Tsuge, Y., Hasunuma, T., Oinuma, K. Takaya, N., and Kondo, A. Simultaneous saccharification and fermentation of kraft pulp by recombinant Escherichia coli for phenyllactic acid production. Biochem. Eng. J. 88, 188-194 (2014)
  • Zhou, S., Narukami, T., Masuo, S., Shimizu, M., Fujita, T., Kamimura, Y., and Takaya, N.: NO-inducible nitrosothionein mediates NO removal in tandem with thioredoxin. Nat. Chem. Biol. 9, 657-663 (2013)
  • Fujita, T., Nguyen, Nieu Duc, Ito, T., Zhou, S., Osada, L., Tateyama, S., Kaneko, T., and Takaya, N.: Microbial monomers custom-synthesized to build true bio-derived aromatic polymers.Appl. Microbiol. Biothechnol. 97, 8887-8894 (2013)
  • Shimizu, M., and Takaya, N.: Nudix hydrolase controls nucleotides and glycolytic mechanisms in hypoxic Aspergillus nidulans. Biosci. Biotechnol. Biochem. 77, 1888-1893 (2013)
  • Sugimoto, N., Takakura, Y., Shiraki, K., Honda, S., Takaya, N., Hoshino, T., and Nakamura, A.: Directed Evolution for Thermostabilization of a Hygromycin B Phosphotransferase from Streptomyces hygroscopicus. Biosci. Biotechnol. Biochem. 77, 2234-2241 (2013)
  • Siriwan, W., Roytrakul, S., Shimizu, M., Takaya, N., and Chowpongpang, S.: Proteomics of papaya ringspot virus-infected papaya leaves. Kasetsart J. (Nat. Sci.) 47, 589-602 (2013)
  • Shimizu, M., Masuo, S., Fujita, T., Doi, Y., Kamimura, Y., Takaya, N.: Hydrolase controls cellular nicotinamide adenine dinucleotide, sirtuin and secondary metabolites. Mol. Cell. Biol. 32, 3743-3755 (2012)
  • Shimizu, T., Takaya, N., Nakamura, A.: An L-glucose catabolic pathway in Paracoccus sp. 43P, J. Biol. Chem. 287, 40448-40456 (2012)
  • Taniyama, K., Sasaki, Y., Toyofuku, M., Nomura., N., Itoh, H., Hoshino, T., and Takaya, N.: Group X aldehyde dehydrogenases of Pseudomonas aeruginosa PAO1 degrade hydrazones. J. Bacteriol.194, 1447-1456 (2012)
  • Zhou, S., Narukami, T., Nameki, M., Ozawa, T., Kamimura,Y., Hoshino, T., and Takaya, N.: Heme-biosynthetic porphobilinogen deaminase protects Aspergillus nidulans from nitrosative stress. Appl. Environ. Microbiol. 78, 103-109 (2012)
  • Terabayashi, Y., Shimizu, M., Kitazume, T., Masuo, S., Fujii, T., and Takaya, N.: Conserved and specific responses to hypoxia in Aspergillus oryzae and Aspergillus nidulans determined by comparative transcriptomics. Appl. Microbiol. Biothechnol. 93, 305-317 (2012)
  • Fujii, T., Shimizu, M., Doi, Y., Fujita, T., Ito, T., Miura, D., Wariishi, and Takaya, N.: Novel fungal phenylpyruvate reductase belongs to D-isomer-specific 2-hydroxyacid dehydrogenase family. Biochim. Biophys. Acta. 1814, 1669-1676 (2011)
  • Sato, I., Shimatani, K., Fujita, K., Abe, T., Shimizu, M., Fujii, T., Hoshino, T., and Takaya, N.: Glutathione reductase/glutathione is responsible for cytotoxic elemental sulfur tolerance via polysulfide shuttle in fungi J. Biol. Chem. 286, 20283-20291 (2011)